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Somatic structural variation and cancer
2015
Briefings in Functional Genomics
With the advent of next-generation sequencing technologies, we have witnessed a rapid pace of discovery of new patterns of somatic structural variation in cancer genomes, and an attempt to figure out their underlying mechanisms. Some of these mechanisms are associated with particular cancer types, and in some cases are the main cause of the structural mutations that drive the oncogenic process. This review provides an overview of the patterns of somatic structural variation and chromosomal
doi:10.1093/bfgp/elv016
pmid:25903743
fatcat:2k5n236vajetllt2pxv5ujyxhq