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Systems metabolic engineering: Genome-scale models and beyond
2010
Biotechnology Journal
The advent of high throughput genome-scale bioinformatics has led to an exponential increase in available cellular system data. Systems metabolic engineering attempts to use data-driven approaches -based on the data collected with high throughput technologies -to identify gene targets and optimize phenotypical properties on a systems level. Current systems metabolic engineering tools are limited for predicting and defining complex phenotypes such as chemical tolerances and other global,
doi:10.1002/biot.200900247
pmid:20151446
pmcid:PMC2911524
fatcat:kcqqwagubfgavpoh65u2xy7g3y