Angiogenesis index CD105 (endoglin)/CD31 (PECAM-1) as a predictive factor for invasion and proliferation in intraductal papillary mucinous neoplasm (IPMN) of the pancreas

Michael Tachezy, Uta Reichelt, Tanja Melenberg, Florian Gebauer, Jakob R Izbicki, Jussuf T Kaifi
2010 Histology and Histopathology  
Neovascularisation plays an important role in the tumorigenesis of invasive IPMN of the pancreas, and therefore angiogenesis-associated molecules like CD105 and CD31 might be useful tools as prognostic markers. Furthermore, the results indicate a potential role for adjuvant anti-angiogenic therapies in selected patients with recurring and/or invasive IPMN of the pancreas.
doi:10.14670/hh-25.1239 pmid:20712008 fatcat:juup4rfffzdcjg44bs5j7mgsm4