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The impacts of prolonged visual display terminal (VDT) work on central nervous system and autonomic nervous system are observed and analyzed based on electroencephalogram (EEG) and heart rate variability (HRV). Power spectral indices of HRV, the P300 components based on visual oddball task, and multichannel linear descriptors of EEG are combined to estimate the change of mental fatigue. The results show that long-term VDT work induces the mental fatigue. The power spectral of HRV, the P300doi:10.1155/2008/185638 fatcat:e5kzjqnb3rgdrk5br6zpunhrmy