GlimmerM, Exonomy and Unveil: three ab initio eukaryotic genefinders

W. H. Majoros
2003 Nucleic Acids Research  
We present three programs for ab initio gene prediction in eukaryotes: Exonomy, Unveil and GlimmerM. Exonomy is a 23-state Generalized Hidden Markov Model (GHMM), Unveil is a 283-state standard Hidden Markov Model (HMM) and GlimmerM is a previously-described genefinder which utilizes decision trees and Interpolated Markov Models (IMMs). All three are readily re-trainable for new organisms and have been found to perform well compared to other genefinders. Results are presented for Arabidopsis
more » ... liana. Cases have been found where each of the genefinders outperforms each of the others, demonstrating the collective value of this ensemble of genefinders. These programs are all accessible through webservers at http:// www.tigr.org/software.
doi:10.1093/nar/gkg527 pmid:12824375 pmcid:PMC168934 fatcat:f56fqvuyjbccbecu6dw642yara