Hypereosinophilia Associated with Increased Serum Levels of Carcinoembryonic Antigen

Hiroka Iwata, Nobuo Tsuboi, Takeo Ishii, Yoichiro Hara, Ichiro Okido, Hajime Takahashi, Tetsuya Kawamura, Tatsuo Hosoya
2008 Internal medicine (Tokyo. 1992)  
We report a case of hypereosinophilia associated with increased serum levels of carcinoembryonic antigen (CEA). The patient developed fever, diarrhea, erythroderma and eosinophilia. Disorders known to be associated with eosinophilia were not detected. The typical malignant diseases related to a rise in CEA levels were not identified. The CEA value reached a maximum of 81.4 ng/ml a few weeks late for the peak of the eosinophilic count. Corticosteroid therapy was effective in improving clinical
more » ... mproving clinical symptoms and the CEA values decreased in association with the improvement of those manifestations, suggesting a pathophysiological link between the disease activity of hypereosinophilia and the changes in CEA level.
doi:10.2169/internalmedicine.47.0611 pmid:18480583 fatcat:itqybngopveq5nbk5lemx5iwiq