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Random versus Cell Cycle-Regulated Replication Initiation in Bacteria: Insights from Studying Vibrio cholerae Chromosome 2
2016
Microbiology and Molecular Biology Reviews
SUMMARY Bacterial chromosomes initiate replication at a fixed time in the cell cycle, whereas there is generally no particular time for plasmid replication initiation or chromosomal replication initiation from integrated plasmids. In bacteria with divided genomes, the replication system of one of the chromosomes typically resembles that of bacteria with undivided genomes, whereas the remaining chromosomes have plasmid-like replication systems. For example, in Vibrio cholerae , a bacterium with
doi:10.1128/mmbr.00033-16
pmid:27903655
pmcid:PMC5312244
fatcat:ud7rj5xzgnhidj5qtpfw23esgu