Annually, 30,000 Mexicans are diagnosed with hematological diseases, of which about 18,000 must undergo hematopoietic stem cell transplantation as the only opportunity to live and improve their quality of life. In this specialized medical procedure, psychosocial factors associated with biopsychosocial vulnerability, therapeutic adherence, final results of transplantation and survival interact, hence the importance of psychosocial evaluation. The objective of this article was to integrate and

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... cribe a psychological evaluation protocol aimed at the transplant candidate. From the search and free review of theoretical and applied articles in different bases, a brief evaluation guide was pointed out and it is concluded that its application facilitates the work of the psychologist in the context of hematological transplantation, favors the adaptation of the recipient, donor patient and his family and contributes to the improvement of the quality of life.