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Short Communication: Subcellular Motion Compensation for Minimally Invasive Microscopy, In Vivo: Evidence for Oxygen Gradients in Resting Muscle
2010
Circulation Research
Rationale: In vivo microscopy seeks to observe dynamic subcellular processes in a physiologically relevant context. A primary limitation of optical microscopy in vivo is tissue motion, which prevents physiological time course observations or image averaging. Objective: To develop and demonstrate motion compensation methods that can automatically track image planes within biological tissues, including the tissue displacements associated with large changes in blood flow, and to evaluate the
doi:10.1161/circresaha.109.211946
pmid:20167928
pmcid:PMC3209509
fatcat:dyg3jj6ukzg4tp2opy6slezkcm