In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets

Hindustan Abdul Ahad, Dept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous,Ananthapuramu 515721, Andhra Pradesh, India., Chinthaginjala Haranath, Rahul Raghav Dasari, Madana Gowthami, Naga Jyothi Varam, Pandyala Sravanthi, Dept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous,Ananthapuramu 515721, Andhra Pradesh, India., Dept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous,Ananthapuramu 515721, Andhra Pradesh, India., Dept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous,Ananthapuramu 515721, Andhra Pradesh, India., Dept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous,Ananthapuramu 515721, Andhra Pradesh, India., Dept. of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) - Autonomous,Ananthapuramu 515721, Andhra Pradesh, India.
2020 Maǧallaẗ Al-Kuwayt li-l-ʿulūm  
The present work is a comparative exploration of some of the physicochemical possessions like weight change, thickness, diameter, hardness, disintegration time, in vitro drug discharge, and analysis studies of various commercially available Pantoprazole sodium tablets (PST) containing 40 mg of drug. The hardness, loss on friability, dissolution test, disintegration test, and uniformity of drug content were evaluated. All the brands meet the requirements as per the pharmacopoeial standards. The
more » ... issolution profile study revealed that PST-1 was faster, while PST-2 was slower. The dissolution information was kinetically treated.
doi:10.48129/kjs.v48i1.8598 fatcat:uhsznyynbrcabozxmuygedp6oq