Inverse Treatment Planning for Radiation Therapy Based on Fast Monte Carlo Dose Calculation [chapter]

M. Fippel, M. Alber, M. Birkner, W. Laub, F. Nüsslin, I. Kawrakow
2001 Advanced Monte Carlo for Radiation Physics, Particle Transport Simulation and Applications  
An inverse treatment planning system based on fast Monte Carlo (MC) dose calculation is presented. It allows optimisation of intensity modulated dose distributions in 15 to 60 minutes on present day personal computers. If a multi-processor machine is available, parallel simulation of particle histories is also possible, leading to further calculation time reductions. The optimisation process is divided into two stages. The first stage results in fluence profiles based on pencil beam (PB) dose
more » ... lculation. The second stage starts with MC verification and post-optimisation of the PB dose and fluence distributions. Because of the potential to accurately model beam modifiers, MC based inverse planning systems are able to optimise compensator thicknesses and leaf trajectories instead of intensity profiles only. The corresponding techniques, whose implementation is the subject for future work, are also presented here.
doi:10.1007/978-3-642-18211-2_36 fatcat:lfuv773ygvhl5fj7xg25j3fwgq