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Human-mouse genome comparisons to locate regulatory sites
2000
Nature Genetics
Elucidating the human transcriptional regulatory network 1 is a challenge of the post-genomic era. Technical progress so far is impressive, including detailed understanding of regulatory mechanisms for at least a few genes in multicellular organisms 2-4 , rapid and precise localization of regulatory regions within extensive regions of DNA by means of cross-species comparison 5-7 , and de novo determination of transcription-factor binding specificities from large-scale yeast expression data 8 .
doi:10.1038/79965
pmid:11017083
fatcat:bz6mrkcrdfeifnbri5iibc372i