IMI – Myopia Genetics Report

Milly S. Tedja, Annechien E. G. Haarman, Magda A. Meester-Smoor, Jaakko Kaprio, David A. Mackey, Jeremy A. Guggenheim, Christopher J. Hammond, Virginie J. M. Verhoeven, Caroline C. W. Klaver
2019 Investigative Ophthalmology and Visual Science  
Citation: Tedja MS, Haarman AEG, Meester-Smoor MA, et al.; for the CREAM Consortium. IMI -Myopia Genetics Report. Invest Ophthalmol Vis Sci. 2019;60:M89-M105. https:// doi.org/10.1167/iovs.18-25965 2. KEY POINTS 1. Refractive errors including myopia are caused by a complex interplay between many common genetic factors and environmental factors (near work, outdoor exposure). 2. Early linkage studies and candidate gene studies have identified up to 50 loci and genes, but findings remained mostly
more » ... gs remained mostly unverified in replication studies.
doi:10.1167/iovs.18-25965 fatcat:2vkuaaykh5g2ncjkxrbsyyr6cy