Dynamic Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by Competitive Interactions of Molecular Adaptors

Ji Hyun Lee, Wito Richter, Wan Namkung, Kyung Hwan Kim, Eunjoon Kim, Marco Conti, Min Goo Lee
2007 Journal of Biological Chemistry  
2 The abbreviations used are: CFTR, cystic fibrosis transmembrane conductance regulator; AKAP, cAMP-dependent protein kinase-anchoring protein; IBMX, 3-isobutyl-1-methylxanthine; IP, immunoprecipitation; NHE, Na ϩ /H ϩ exchanger; NTA, Ni 2ϩ -nitrilotriacetic acid; PDE, phospho-diesterase; PKA, cAMP-dependent protein kinase; PDZ, PSD-95/discs large/ZO-1; PSD, postsynaptic density; SPR, surface plasmon resonance; CHO, Chinese hamster ovary; GST, glutathione S-transferase; PR, proline-rich; UCR, upstream conserved region.
doi:10.1074/jbc.m610857200 pmid:17244609 fatcat:2z63qbd4xba3bfacueksn2uulu