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Benzimidazoles derivatives with (2-{6-Chloro-5-nitro-1-[2-(1H-tetrazol-5-yl) biphenyl-4-ylmethyl] 1H-benzoimidazol-2-yl}-phenyl)-(substituted-benzylidene)-amine with potential angiotensin II receptor antagonists as antihypertensive activity
2010
International Journal of Drug Delivery
Preserved Fulltext
In this study we have synthesized some Benzimidazole derivatives biphenyl-4-ylmethyl] 1Hbenzoimidazol-2-yl}-phenyl)-(Substituted-benzylidene)-amine and screened for their antihypertensive activity. 4-chloro-o-Phenylenediamine was condensed with anthranilic acid in presence of Polyphosphoric acid and different aryl aldehydes compounds with biphenyl tetrazole ring. The presence of specific functional group were analysed by IR spectroscopy, The determination of structure for the synthesized
doi:10.5138/ijdd.2010.0975.0215.02033
fatcat:z7nri5u3nfcg7axrky3jazfchy