COPASI and its applications in biotechnology

Frank T. Bergmann, Stefan Hoops, Brian Klahn, Ursula Kummer, Pedro Mendes, Jürgen Pahle, Sven Sahle
2017 Journal of Biotechnology  
A B S T R A C T COPASI is software used for the creation, modification, simulation and computational analysis of kinetic models in various fields. It is open-source, available for all major platforms and provides a user-friendly graphical user interface, but is also controllable via the command line and scripting languages. These are likely reasons for its wide acceptance. We begin this review with a short introduction describing the general approaches and techniques used in computational
more » ... ng in the biosciences. Next we introduce the COPASI package, and its capabilities, before looking at typical applications of COPASI in biotechnology.
doi:10.1016/j.jbiotec.2017.06.1200 pmid:28655634 pmcid:PMC5623632 fatcat:uebyrccn6rfhpnrj4sx6o3dmai