PGx: Putting Peptides to BED

Manor Askenazi, Kelly V. Ruggles, David Fenyö
2015 Journal of Proteome Research  
Every molecular player in the cast of biology's central dogma is being sequenced and quantified with increasing ease and coverage. To bring the resulting genomic, transcriptomic, and proteomic data sets into coherence, tools must be developed that do not constrain data acquisition and analytics in any way but rather provide simple links across previously acquired data sets with minimal preprocessing and hassle. Here we present such a tool: PGx, which supports proteogenomic integration of mass
more » ... ectrometry proteomics data with next-generation sequencing by mapping identified peptides onto their putative genomic coordinates.
doi:10.1021/acs.jproteome.5b00870 pmid:26638927 pmcid:PMC4782174 fatcat:kv6zfpcdbnfrbkanxucashi75u