IgG4-related Disease Presenting as a Symptomatic Tumor-like Lesion in the Posterior Fossa : Case Report
症候性後頭蓋窩腫瘤として発症したIgG4関連疾患の1例

Taro Suzuki, Tsukasa Wada, Kuniaki Ogasawara, Yuichi Sato, Noriyuki Uesugi, Akira Kurose, Akira Ogawa
2012 Japanese Journal of Neurosurgery  
IgG4 − related disease is often characterized by hypophysitis or pachymeningitis . A 63 − year − old man pre − sented with dysphagia and left hemiparesis . Magnetic resonance { maging demonstrated a tumor located at the bi互 ateral jugular foramina that compressed the medulla oblongata , and thickened dura mater in the bilateral cav − ernous sinuses was also observed . Left subocc 孟 pital craniotomy was performed , and the tumor was confirmed to have originated from the left jugular foramen to
more » ... ugular foramen to involve the glossopharyngeal and vagal nerves ・ Histopathological examination of the surgical specimen showed massive infiltration of IgG4 − positive lymphocytes and plasnla cells , Based on these histopathological findings and extreme elevation of serum IgG4, the patient was diagnosed wlth IgG4 − related disease . IgG4 − related disease can include the development of symptomatic tumor − like lesions in the posterior fossa . (
doi:10.7887/jcns.21.571 fatcat:bwwrdmjw2rhnjk7vza4gmrgnxy