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Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein sigma 1
1995
Journal of Virology
Reoviruses are important models for studies of viral pathogenesis; however, the mechanisms by which these viruses produce cytopathic effects in infected cells have not been defined. In this report, we show that murine L929 (L) cells infected with prototype reovirus strains type 1 Lang (T1L) and type 3 Dearing (T3D) undergo apoptosis and that T3D induces apoptosis to a substantially greater extent than T1L. Using T1L ؋ T3D reassortant viruses, we found that differences in the capacity of T1L and
doi:10.1128/jvi.69.11.6972-6979.1995
fatcat:ei2f7nmhlbgnzhjfgrt67fp2fe