A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit <a rel="external noopener" href="https://biomedres.us/pdfs/BJSTR.MS.ID.004494.pdf">the original URL</a>. The file type is <code>application/pdf</code>.
"A Review of Computational Fluid Dynamics (CFD) Simulations of Mixing in the Pharmaceutical Industry"
<span title="2020-05-01">2020</span>
<i title="Biomedical Research Network, LLC">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/7skyhy7ghvel3niw4nxm3qyija" style="color: black;">Biomedical Journal of Scientific & Technical Research</a>
</i>
Preserved Fulltext
Due to the increasing computational power and availability of advanced commercial, as well as open-source computational fluid dynamics (CFD) software, performing CFD simulations is becoming more accessible and its use has expanded into many industrial sectors. For the pharmaceutical industry, the topic of mixing is especially of interest, since it is a common unit operation in pharmaceutical processes and empirical and semi-empirical correlations for predicting the hydrodynamic characteristics
<span class="external-identifiers">
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.26717/bjstr.2020.27.004494">doi:10.26717/bjstr.2020.27.004494</a>
<a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/d4eahxrm45gkbciia6rqt6qdlu">fatcat:d4eahxrm45gkbciia6rqt6qdlu</a>
</span>
more »
... nside a batch mixing vessel do not consider the complete three-dimensional geometry of the vessel and impeller. This is important in processes such as crystallization, dissolution, compounding, and cellular production in bioreactors, and the obtained information can aid in the selection of the mixer geometry, the choice of mixing speed and for achieving comparable scale-up/down operation of laboratory and industrial mixing vessels. The pharmaceutical industry is not keen on publishing their research and the details of their technology, so the available literature is limited. In this mini review, publications, in which CFD simulations of the mixing process were performed for real pharmaceutical cases are presented, the obtained results are discussed and the software, modeling techniques and methods and their comparisons to measurements are highlighted.
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200709143754/https://biomedres.us/pdfs/BJSTR.MS.ID.004494.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext">
<button class="ui simple right pointing dropdown compact black labeled icon button serp-button">
<i class="icon ia-icon"></i>
Web Archive
[PDF]
<div class="menu fulltext-thumbnail">
<img src="https://blobs.fatcat.wiki/thumbnail/pdf/05/2f/052f5fcb8ba0f64ec5bc0ee62f14adc25b5a71bb.180px.jpg" alt="fulltext thumbnail" loading="lazy">
</div>
</button>
</a>
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.26717/bjstr.2020.27.004494">
<button class="ui left aligned compact blue labeled icon button serp-button">
<i class="external alternate icon"></i>
Publisher / doi.org
</button>
</a>