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Consensus transcriptional states describe human mononuclear phagocyte diversity in the lung across health and disease
[article]
2020
bioRxiv
pre-print
Monocytes, dendritic cells, and macrophages, commonly referred to as mononuclear phagocytes (MNPs), are innate immune cells capable of adopting diverse homeostatic and pathogenic phenotypes. Recent single-cell RNA-sequencing studies across many diseases in the lung have profiled this diversity transcriptionally, defining new cellular states and their association with disease. Despite these massive cellular profiling efforts, many studies have focused on defining myeloid dysfunction in specific
doi:10.1101/2020.08.06.240424
fatcat:fkjigip3xjaazovitynkbjjbmu