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Biosynthesis of very long-chain fatty acids (C>24) in Atlantic salmon: Cloning, functional characterisation, and tissue distribution of an Elovl4 elongase
2011
Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology
The elongases of very long-chain fatty acids (Elovl) account for the rate-limiting condensation step of the elongation process in fatty acid (FA) biosynthesis in vertebrates. One member of the Elovl family, Elovl4, has been regarded as a critical enzyme in vertebrates in the production of the so-called very long-chain fatty acids (VLC-FA), a group of compounds that have been scarcely explored in fish. Here we report on the cloning of a novel elovl4-like elongase from Atlantic salmon. The salmon
doi:10.1016/j.cbpb.2011.02.007
pmid:21377536
fatcat:mryl37eyzjeuti3i5vjfrakgfu