Predictors of 30-day and 1-year mortality after transvenous lead extraction: a single-centre experience

S. Deckx, T. Marynissen, F. Rega, J. Ector, D. Nuyens, H. Heidbuchel, R. Willems
2014 Europace  
Aims Owing to the increasing use of cardiac implantable electronic devices, there is a growing need for safe and effective techniques to manage device-related complications and lead dysfunction. Lead extraction remains a challenging procedure with inherent risks. We present the 30-day and long-term outcomes of lead extractions in the University Hospitals Leuven. Methods and results We report a retrospective cohort study of 176 patients admitted to the University Hospitals Leuven between January
more » ... 2005 and December 2011, for the transvenous extraction of 295 leads. Indications for extraction were lead dysfunction and device upgrade in 84 (47.7%), pocket infection in 61 (34.7%), and systemic infection in 31 patients (17.6%). Extraction was successful in 95.5% of patients with complete removal of the leads or only a minor fragment remaining. One fatal periprocedural complication occurred. Thirty-day mortality was 3.4% (n ¼ 6). Systemic infection was the only significant predictor of 30-day mortality [odds ratio (OR) 29.706; P ¼ 0.029]. A lower level of haemoglobin prior to extraction also tended to be related with a higher mortality, but this was not significant (OR 2.024; P ¼ 0.082). One-year mortality was 8.5% (n ¼ 15). Systemic infection (OR 9.727; P ¼ 0.009), a lower level of haemoglobin (OR 1.597; P ¼ 0.05), and a higher level of ureum (OR 1.021; P ¼ 0.017) prior to extraction were significant predictors of 1-year mortality. Systemic infection was associated with significantly higher 30-day (19%), 1-year (32%), and long-term (39%) mortality rates. Conclusion Lead extraction can be safely and successfully performed in the majority of patients, with limited life-threatening complications. However, lead extraction because of systemic infection is associated with a significantly higher risk of short-and
doi:10.1093/europace/eut410 pmid:24569572 fatcat:pmos3i2dhjb3xmc4lzfi3hihlq