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SVAT: Secure Outsourcing of Variant Annotation and Genotype Aggregation
Sequencing of thousands of samples provides genetic variants with allele frequencies spanning a very large spectrum and gives invaluable insight for genetic determinants of diseases. Protecting the genetic privacy of participants is challenging as only a few rare variants can easily re-identify an individual among millions. In certain cases, there are policy barriers against sharing genetic data from indigenous populations and stigmatizing conditions. Results: We present SVAT, a method fordoi:10.1101/2021.09.28.462259 fatcat:sm2emd7ygfgc3azdl4t7nmy6gq