The brown tumor or fibrocystic osteitis is a rare bone lesion secondary to hyperparathyroidism. It can affect the whole bone skeleton with sometimes-infrequent locations. We present a case of multiple brown tumors with unusual bone localization revealed by a phosphocalcic metabolic disorder and primary hyperparathyroidism. After hypocalcemic medical treatment and targeted parathyroid surgery, the evolution was favorable with immediate normalization of parathyroid hormone.This case focuses on

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... role of 99mTc-Sestamibi functional imaging to optimize the diagnostic orientation and therapeutic strategy of this type of tumor.