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Voxelwise gene-wide association study (vGeneWAS): Multivariate gene-based association testing in 731 elderly subjects
2011
NeuroImage
Imaging traits provide a powerful and biologically relevant substrate to examine the influence of genetics on the brain. Interest in genome-wide, brain-wide search for influential genetic variants is growing, but has mainly focused on univariate, SNP-based association tests. Moving to gene-based multivariate statistics, we can test the combined effect of multiple genetic variants in a single test statistic. Multivariate models can reduce the number of statistical tests in gene-wide or
doi:10.1016/j.neuroimage.2011.03.077
pmid:21497199
pmcid:PMC3366726
fatcat:plqqxysutvgbjn3ue3prfgk7gi