Histochemical Study of Acetylcholinesterase Activity in Rectal Suction Biopsy Speciments of Hirschsprung Disease
Hirschsprung病における吸引生検直腸粘膜内Acetycholinesterase活性の組織化学的検索

Yoshiko AGATSUMA, Akira SUGIYAMA, Katsumi IWATA
Bulletin of Kochi Gakuen College  
Recta]mucosal suction biopsy specimens from a series of 16 infants and children with cnstipation and other gastrointestinal problems , were stained with a sensitive acetylcholinesterase ( AchE ) method . In 8 cases there was an increase in numbers and sizes of cholinergic nerves in the larnina propria and musclaris mucosae and submucosae , These data demonstrate that an abnormal pattern Qf AchE reaction is diagnostic of aganglionic rnegacolon . There − fQre these methods are useful for diagnosis of Hirschsprung ' s disease . 緒 言
doi:10.24649/kgc.20.0_469 fatcat:kdvjwdnxrna2jbbggijfatj4ny