Plasma Leptin Concentration in Dogs with Diabetes Mellitus

Naohito NISHII, Miho YAMASAKI, Masaki TAKASU, Tsutomu HONJOH, Haruki SHIBATA, Yoshihiko OTSUKA, Satoshi TAKASHIMA, Yasunori OHBA, Hitoshi KITAGAWA
2010 Journal of Veterinary Medical Science  
The plasma leptin concentration was evaluated in dogs with diabetes mellitus. Twenty normal and sixteen diabetic dogs were divided into nonobese and obese groups based on body condition score, respectively. The obese normal dogs had significantly higher plasma leptin concentrations than the nonobese normal dogs, whereas there was no significant difference between the nonobese and obese diabetic dogs. In addition, the plasma leptin concentration in the obese diabetic dogs was significantly lower
more » ... significantly lower than that in the obese normal dogs. In conclusion, the plasma leptin concentrations in the diabetic dogs were affected by factors other than adiposity.
doi:10.1292/jvms.09-0481 pmid:20145380 fatcat:dnoskhtqdjdendup3pdcfzq7pq