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To review the aetiology, diagnosis, and management of Parkinson's disease, with a local perspective. Medline from 1966 onwards, and all major neurological journals and movement disorder journals were searched for evidence on the aetiology, diagnosis, and management of Parkinson's disease. Key words for the literature search were "Parkinson's disease" and "Chinese" or "Hong Kong". All relevant articles in English were reviewed. The number of promising genes for familial Parkinson's disease ispmid:16340025 fatcat:agotntx2frdzfdcybhruhhbgea