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miR-9 is a tumor suppressor in pediatric AML with t(8;21)
2013
Leukemia
MicroRNAs (miRNAs) play a pivotal role in the regulation of hematopoiesis and development of leukemia. Great interest emerged in modulating miRNA expression for therapeutic purposes. In order to identify miRNAs, which specifically suppress leukemic growth of acute myeloid leukemia (AML) with t(8;21), inv(16) or mixed lineage leukemia (MLL) rearrangement by inducing differentiation, we conducted a miRNA expression profiling in a cohort of 90 cytogenetically characterized, de novo pediatric AML
doi:10.1038/leu.2013.357
pmid:24270738
fatcat:ie4sb4hrubb4hbukuliv7ilnwy