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The effect of glycerol on signal supression during electrospray ionization analysis of proteins
2004
Spectroscopy (Ottawa)
The effect of salts, detergents and chaotropic agents on mass spectrometric analysis are relatively well understood, mainly due to their actions decreasing the performance of ESI interface in mass spectrometric analysis. However, there are few studies in the literature characterizing the effect of protein stabilization by glycerol, followed in some circumstances by the suppression of protein signal when ESI interface is used. The aim of the present research was to investigate in details the
doi:10.1155/2004/732938
fatcat:jrqjbcgqgra7vbe6nmfw6uatby