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Claudin-4 is required for vasculogenic mimicry formation in human breast cancer cells
2015
OncoTarget
Vasculogenic mimicry (VM) refers to the unique capability of aggressive tumor cells to mimic the pattern of embryonic vasculogenic networks. Claudins are aberrantly expressed in aggressive breast cancer. However, the relationship between claudins and VM formation is not clear. We examined VM in two human breast cancer cell lines with different aggressive capabilities (MDA-MB-231 and MCF-7 cells) and one human umbilical vein endothelial cell line (HUVEC). Both HUVEC and MDA-MB-231 cells formed
doi:10.18632/oncotarget.3571
pmid:25871476
pmcid:PMC4484441
fatcat:3f5wlt2quffv5m3c3kblrltjzy