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La Crosse virus nucleocapsid protein controls its own synthesis in mosquito cells by encapsidating its mRNA
1989
Journal of Virology
Within 24 to 48 h of La Crosse virus infection of mosquito cells, >75% of the S mRNA was found to band in CsCl density gradients at the position of genome or antigenome nucleocapsids. The encapsidation of the S mRNA correlates with the repression of N protein synthesis in vivo, and the encapsidated S mRNA cannot be translated in vitro. Unlike genome and antigenome assembly, S mRNA assembly is a relatively slow process, which is not coupled to its synthesis. Within the encapsidated S mRNA
doi:10.1128/jvi.63.12.5166-5174.1989
fatcat:n5vxncbymnegxgp5xc42xnolgm