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Visualisation of the T cell differentiation programme by Canonical Correspondence Analysis of transcriptomes
2014
BMC Genomics
Currently, in the era of post-genomics, immunology is facing a challenging problem to translate mutant phenotypes into gene functions based on high-throughput data, while taking into account the classifications and functions of immune cells, which requires new methods. Results: Here we propose a novel application of a multidimensional analysis, Canonical Correspondence Analysis (CCA), to reveal the molecular characteristics of undefined cells in terms of cellular differentiation programmes by
doi:10.1186/1471-2164-15-1028
pmid:25428805
pmcid:PMC4258272
fatcat:fsyvuw2ajfgazdjjymqtryth5e