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TSSi—an R package for transcription start site identification from 5′ mRNA tag data
Computer applications in the biosciences : CABIOS
High-throughput sequencing has become an essential experimental approach for the investigation of transcriptional mechanisms. For some applications like ChIP-seq, several approaches for the prediction of peak locations exist. However, these methods are not designed for the identification of transcription start sites (TSSs) because such datasets contain qualitatively different noise. In this application note, the R package TSSi is presented which provides a heuristic framework for thedoi:10.1093/bioinformatics/bts189 pmid:22513994 fatcat:xrtefpedjzeqreqfojf3wzr4pa