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Molecular evidences on the benefit of N-acetylcysteine in experimental colitis
2008
Open Life Sciences
AbstractInflammatory bowel disease (IBD) is a chronic recurrent disease of the digestive tract with an unknown etiology. The aim of this study was to examine the possible protective effects of N-acetylcysteine (NAC) in the mouse model of IBD by measuring specific biomarkers in the colon cells. Colitis was induced by administration of dextran sodium sulfate (DSS) in drinking water (3%) for 7 days. Three doses of NAC (106, 160, and 240 mg/kg) were given after induction of colitis (4 days post
doi:10.2478/s11535-008-0005-x
fatcat:y6aqwzkpercc7jzy3mmgvoizsi