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Structural changes in dividing sea-urchin eggs induced by the volatile anaesthetic halothane
1982
Journal of Cell Science
Fertilized Lytechinus eggs exposed to the volatile anaesthetic halothane before metaphase do not undergo cytoplasmic cleavage. This effect has been correlated with the failure of the contractile ring to assemble. Comparative studies on mitotic apparatuses isolated from control and halothane-treated cells show that halothane significantly impairs both spindle and aster growth as early as metaphase. When transferred to control solutions, halothane-treated cells initiate furrowing activity in
pmid:7202012
fatcat:gopds2vub5b2basinfrvwx6xyi