Resources for Functional Genomics Studies in Drosophila melanogaster

Stephanie E. Mohr, Yanhui Hu, Kevin Kim, Benjamin E. Housden, Norbert Perrimon
2014 Genetics  
Drosophila melanogaster has become a system of choice for functional genomic studies. Many resources, including online databases and software tools, are now available to support design or identification of relevant fly stocks and reagents or analysis and mining of existing functional genomic, transcriptomic, proteomic, etc. datasets. These include large community collections of fly stocks and plasmid clones, "meta" information sites like FlyBase and FlyMine, and an increasing number of more
more » ... ialized reagents, databases, and online tools. Here, we introduce key resources useful to plan large-scale functional genomics studies in Drosophila and to analyze, integrate, and mine the results of those studies in ways that facilitate identification of highest-confidence results and generation of new hypotheses. We also discuss ways in which existing resources can be used and might be improved and suggest a few areas of future development that would further support large- and small-scale studies in Drosophila and facilitate use of Drosophila information by the research community more generally.
doi:10.1534/genetics.113.154344 pmid:24653003 pmcid:PMC4012471 fatcat:7n7iwcdva5bbxe2ewwdv3ny4d4