The method of closed single layer-to-layer anastomosis of the digestive tract, that was developed by Matsubayashi in 1976, has been used for every anastomosis of the digestive tract in our department. In the present study, clinical results from this surgical technique used for anastomosis of the large intestine were investigated. The method was also compared with the Albert-Lembert (A-L) method in animal experiments. Operative results were more favorable with this method than with the A-L

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... , especially in cases of colocolostomy and colorectostomy. In the healing of the anastomosed part of the dog colon, prompter healing was found after this method, especially in the mucosa and submucous tissue, than after the A-L method. Moreover, from the bacteriological examination of the tissue in the anastomosed area three days after surgery, this method was more frequently found to be associated with sterility, especially in regard to aerobes, than the A-L method. These results lead us to the conclusion that this method is more useful than the A-L method.