AN OVERVIEW ON ANALYTICAL PROFILE OF VARENICLINE

Vikas G. Mahajan*, Saurabh C. Khadse
2019 Zenodo  
Varenicline is a medicinal agent used to treat smoking addiction. Varenicline is first permitted nicotinic receptor partial agonist. Varenicline is an orally administered α4 andβ2 nicotinic acetylcholine receptor partial agonist. The present study evaluates the various approaches for analysis of VRC in bulk drug as well as formulated products. A short review characterize the collection and discussion of about more than 23 analytical methods which includes HPLC, UPLC, capillary zone
more » ... y zone electrophoresis, liquid-chromatography mass-spectroscopy methods (LC-MS)and UV-Spectrophotometry methods implemented for investigation of VRC in pharmaceutical matrix. The proposed review article summarizes different reported methods developed to help researchers in choosing significant parameters for new analytical method of Varenicline. Keywords: Varenicline; method development; HPLC; capillary electrophoresis
doi:10.5281/zenodo.2652872 fatcat:5zefqnqh7feq3excweo7qg6nbu