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In order to develop a computer-aided diagnosis system for histopathological skin cancer diagnosis, segmentation of the epidermis area is the very first and crucial step. An improved computer-aided epidermis segmentation technique for the whole slide skin histopathological image is proposed in this paper. The proposed technique first obtains an initial segmentation result with the help of global thresholding and shape analysis. A template matching method, with adaptive template intensity value,doi:10.1109/embc.2014.6944883 pmid:25571251 dblp:conf/embc/LuM14 fatcat:5yjxrcrdafbelkhzxmlgz4kvvq