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Stimulated Efflux of Amino Acids and Glutathione from Cultured Hippocampal Slices by Omission of Extracellular Calcium
2008
Journal of Biological Chemistry
The extracellular neurochemistry determines normal brain function and the faith of neurons after insults such as stroke. This thesis concerns the effect of extracellular events related to intense neuronal stimulation and stroke, i.e. over-activation of glutamate-receptors and dramatically decreased extracellular Ca 2+ -concentrations, on efflux of neurotoxic and neuroprotective substances. The use of cultured slices of rat hippocampus enabled parallel analysis of efflux in combination with
doi:10.1074/jbc.m704153200
pmid:18272524
pmcid:PMC2447665
fatcat:gh6eih4n65a5reldv6no3fa3nm