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Based on the liquid resonance principle, a novel sensing technology for detecting the blood coagulation was proposed. The course of blood coagulation can alter its inherent properties, such as viscosity and density. As a result, liquid resonance frequency of blood will change with the blood agglomeration. A gold-plated Interdigital Electrode (IDE) was fabricated and a detection system was designed for the acquisition of the frequency. The activated partial thromboplastin time (APTT) wasdoi:10.4028/www.scientific.net/aef.2-3.253 fatcat:idusvrbmgfa3pfqay5rimxeqji