The Effect of Respiratory on Dose Distributions in Radiotherapy of Lung Cancer: A Phantom Study

Sultan DAMGACI, Uğur AKBAŞ, Canan KÖKSAL, Veli ÇAPALI, Murat OKUTAN, Bayram DEMİR
2016 Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi  
Abstract: Internal organ motions are one of the most significant obstacles for radiotherapy, especially in the case of motions caused by respiratory during the lung irradiation. There is no any consensus about the margin limit given for the target volume (Clinical Target Volume-CTV, Planning Target Volume- PTV etc.), especially for tumors located moving organs such as lung. Besides, as far as we know, there is no any systematic phantom study showed the effects of respiratory motions on
more » ... motions on radiotherapy doses depending on PTV margins in the literature. In present study, our aim was to determine the success degree of enlarging the PTV margins on radiotherapy doses during the moving organ irradiations. The study was performed by using GaF-Chromic EBT films placed to a thorax phantom. A cylindrical part within the phantom can move on through craniocaudal direction with a range of 3 cm with 5 sec. period during the irradiation. From the profiles which were obtained from 3 cm moving situations for 3D-Conformal Radiotherapy (3D-CRT), Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) with narrow margins, it was observed that PTV cannot get adequate dose. The irradiation was better for CTV with larger margins but there was still inhomogeneity for PTV. As a consequence, enlarging the margins alone is not a sufficient method against the negative effects of organ motions on the radiotherapy doses. Key words: Radiotherapy, lung movement, respiratory Akciğer Kanseri Radyoterapisinde Solunumun Doz Dağılımlarına Etkisi: Bir Fantom Çalışması Özet: Organ hareketleri, özellikle akciğer ışınlamaları sırasında nefes alıp vermeden kaynaklanan hareketler, radyoterapi için en önemli zorluklardandır. Özellikle akciğer gibi hareketli organlarda bulunan tümörler için hedef hacme (Clinical Target Volume-CTV, Planning Target Volume- PTV) verilecek marj sınırı hakkında herhangi bir fikir birliği yoktur. Bunun yanında, literatürde solunum hareketlerinin PTV marjlarına bağlı olarak radyoterapi dozlarına etkisini [...]
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