Anaplasmosis in dog is caused by Anaplasma phagocytophilum, a gram-negative, mandatory intracellular bacteria. It is transmitted through vector tick. Clinically, the acute bacterial phase is the most common in dogs. Animals with clinical disease due to acute infection often have vague symptoms of the disease, including fever, drowsiness, weakness, loss of appetite, and muscle pain. Hepcidin, on the other hand, is a peptide hormone and also plays a role as a type II acute phase reactant and

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... ator of iron metabolism. The aim of the study was to evaluate the relationship between hepcidin and some anemia parameters in Anaplasma phagocytophilum seropositive dogs and to learn about the use of hepcidin as a biomarker. In the study, a total of 30 dogs, 20 of which were positive for Anaplasma phagocytophilum, and 10 healthy dogs in the control group were used. In both groups, complete blood counts were performed. Hepcidin, iron, ALT, AST and ALP values were also measured in serum samples collected. When the parameters of the control and study groups were evaluated, the difference between iron, hepcidin, ALT, AST, ALP values were found statistically significant (p<0.05). As a result, hepcidin values between the two groups were statistically significant (p<0.05) and it was concluded that hepcidin could be used as a biomarker in the diagnosis of anaplasma infection in dogs with other parameters.