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Elevated basal and post-feed glucagon-like peptide 1 (GLP-1) concentrations in the neonatal period
European Journal of Endocrinology
BackgroundGlucagon-like peptide 1 (GLP-1) is an incretin hormone that stimulates glucose-induced insulin secretion, increases β-cell proliferation, neogenesis and β-cell mass. In adults, plasma concentrations of amidated GLP-1 are typically within the 5–10 pmol/l range in the fasting state and increases to ∼50 pmol/l after ingestion of a mixed meal.Research design and methodsWe measured plasma glucose, insulin and amidated forms of GLP-1 prefeed and then at 20 and 60 min post-feed followingdoi:10.1530/eje-08-0807 pmid:18952761 fatcat:2n6xkx766fgtfftqhev26hzsoi