BACKGROUND Posterior cranial fossa is located between the Foramen Magnum and Tentorium Cerebelli. It contains cerebellum, pons and medulla oblongata. Tumours of posterior cranial fossa can affect any of the above structures and can lead to pressure symptoms, neurological deficits or sometimes even death. This study has been conducted at our tertiary care centre. Aims and Objectives-To know the usefulness of intraoperative squash cytology and its diagnostic accuracy in differentiating posterior

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... ossa lesions in correlation with clinical, radiological and histopathological diagnosis. Newer diagnostic modalities like MRI help in detecting these tumours early. Squash cytology and histopathological study diagnose these lesions accurately, which may benefit the patient for further treatment. MATERIALS AND METHODS This is a retrospective descriptive study. A total of 28 cases of posterior cranial fossa lesions were analysed with squash cytology and histopathology correlation. RESULTS Among the 28 cases analysed, 27 cases (96.4%) showed squash cytology with histopathologic correlation. A case of ependymoma was misdiagnosed as embryonal tumour/ medulloblastoma on squash cytology. Male preponderance was noted. The commonest age group was first decade in this study. Cerebellopontine angle was the most common site of the tumours in our study. CONCLUSION Analysing the posterior fossa tumours by squash cytology along with radioimaging in tumour localising and patient's demographics helped in correct histopathological diagnosis for further management and follow-up. KEY WORDS Posterior Cranial Fossa SOLs, CP Angle, Squash Cytology, Meningioma, Schwannoma, Prognosis. HOW TO CITE THIS ARTICLE: Gollapalli SL, Moula MC, Shriram, et al. Spectrum of posterior cranial fossa space occupying lesionsour experience at a tertiary care centre.