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In vitro inhibitory effects of selected anticholinesterase insecticides on human plasma and erythrocyte cholinesterases and their thermal reactivation
2010
Iraqi Journal of Pharmacy
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The inhibitory effect of a number of locally used organophosphorus and carbamate insecticides on human plasma and erythrocyte were examined in vitro by using the modified electrometric method for determination of cholinesterase (ChE) activity. The negative logarithum of inhibitor concentration required for ٥٠% inhibition (pIC٥٠) was estimated to range between -١٢.٦ to ٢.٤ and between -٨.٥ to -٠.٧٧ for plasma and erythrocyte ChE, respectively. Plasma ChE was more susceptible than erythrocyte ChE
doi:10.33899/iphr.2010.50068
fatcat:5ler3qinqvac7havpwnkte2pcu