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Effect of carnosine treatment on oxidative stress in serum, apoB-containing lipoproteins fraction and erythrocytes of aged rats
2010
Pharmacological Reports
One of the mechanisms underlying the aging process is proposed to be oxidative damage by free radicals. Carnosine (b-alanyl-Lhistidine) is a dipeptide with antioxidant properties. In this study, we investigated the effect of carnosine supplementation on oxidative stress in serum, apoB-containing lipoproteins (LDL + VLDL) and erythrocytes of young and aged rats. At the initiation of the study, young and aged rats were 5 and 22 months old, respectively. Carnosine (250 mg/kg, daily, ip) was
doi:10.1016/s1734-1140(10)70331-5
pmid:20885014
fatcat:z4hshsxrtbfufpw4r7z2hbzuay