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The design and interpretation of self-experimentation need to be integrated with existing scientific knowledge. Otherwise observations on oneself cannot make a creative contribution to the advance of empirical understanding. Seth Roberts is right to argue that experiments on oneself are unduly neglected in contemporary science. Unfortunately, however, Roberts has misapplied scientific method in the studies that he describes running on himself. There are four types of flaw in his claims to havedoi:10.1017/s0140525x04220064 fatcat:kbc7zzui7vccdhh56j6oggrmw4